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SIGNIFICANT ACCOUNTING POLICIES - Grants and participations & Ordinary share warrants classification and measurement (Details) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Jun. 30, 2022
SIGNIFICANT ACCOUNTING POLICIES        
Recognized participations in research and development as a reduction from research and development expenses $ 2,459,000 $ 878,000 $ 571,000  
Outstanding ordinary share warrants 718,964 728,017   2,371,601
Unrecognized tax benefits $ 0 $ 0