The aggregate amount of write-downs for impairments recognized during the period for long lived assets held for use (including those held for disposal by means other than sale).

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 28
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=123570139&loc=d3e3602-108585

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 360
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=109226691&loc=d3e2921-110230

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 360
-SubTopic 10
-Section 45
-Paragraph 4
-URI http://asc.fasb.org/extlink&oid=123351718&loc=d3e2420-110228

Name:	us-gaap_ImpairmentOfLongLivedAssetsHeldForUse
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

SIGNIFICANT ACCOUNTING POLICIES - Property and equipment and impairment (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Property and equipment
Impairment losses	$ 0	$ 0	$ 0
Computers and software
Property and equipment
Estimated useful lives	33 years
Laboratory equipment \| Minimum
Property and equipment
Estimated useful lives	10 years
Laboratory equipment \| Maximum
Property and equipment
Estimated useful lives	15 years
Furniture and office equipment \| Minimum
Property and equipment
Estimated useful lives	7 years
Furniture and office equipment \| Maximum
Property and equipment
Estimated useful lives	15 years
Cars
Property and equipment
Estimated useful lives	20 years
Manufacturing equipment
Property and equipment
Estimated useful lives	10 years