<?xml version="1.0" encoding="UTF-8"?><!-- Produced by edgar-services.com, Advanced Computer Innovations, Inc., Copyright (C) 2024-2026 --><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
	<headerData>
		<submissionType>SCHEDULE 13G</submissionType>
		<filerInfo>
			<filer>
				<filerCredentials>
					<cik>0002116034</cik>
					<ccc>XXXXXXXX</ccc>
				</filerCredentials>
			</filer>
			<liveTestFlag>LIVE</liveTestFlag>



		</filerInfo>
	</headerData>
	<formData>
		<coverPageHeader>
			<securitiesClassTitle>Common Stock</securitiesClassTitle>
			<eventDateRequiresFilingThisStatement>02/19/2026</eventDateRequiresFilingThisStatement>
			<issuerInfo>
				<issuerCik>0001870404</issuerCik>
				<issuerName>CERO THERAPEUTICS HOLDINGS, INC.</issuerName>
				<issuerCusip>15687V102</issuerCusip>
				<issuerPrincipalExecutiveOfficeAddress>
					<com:street1>201 HASKINS WAY</com:street1>
					<com:street2>SUITE 230</com:street2>
					<com:city>SOUTH SAN FRANCISCO</com:city>
					<com:stateOrCountry>CA</com:stateOrCountry>
					<com:zipCode>94080</com:zipCode>
				</issuerPrincipalExecutiveOfficeAddress>
			</issuerInfo>
			<designateRulesPursuantThisScheduleFiled>
				<designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
			</designateRulesPursuantThisScheduleFiled>
		</coverPageHeader>
		<coverPageHeaderReportingPersonDetails>

			<reportingPersonName>Tibbs Isaiah</reportingPersonName>
			<citizenshipOrOrganization>X1</citizenshipOrOrganization>
			<reportingPersonBeneficiallyOwnedNumberOfShares>
				<soleVotingPower>1830007</soleVotingPower>
				<sharedVotingPower>0</sharedVotingPower>
				<soleDispositivePower>1830007</soleDispositivePower>
				<sharedDispositivePower>0</sharedDispositivePower>
			</reportingPersonBeneficiallyOwnedNumberOfShares>
			<reportingPersonBeneficiallyOwnedAggregateNumberOfShares>1830007</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
			<classPercent>8.67</classPercent>
			<typeOfReportingPerson>IN</typeOfReportingPerson>
		</coverPageHeaderReportingPersonDetails>
		<items>
			<item1>
				<issuerName>CERO THERAPEUTICS HOLDINGS, INC.</issuerName>
				<issuerPrincipalExecutiveOfficeAddress>201 HASKINS WAY, SUITE 230, SOUTH SAN FRANCISCO, CALIFORNIA 94080</issuerPrincipalExecutiveOfficeAddress>
			</item1>
			<item2>
				<filingPersonName>Tibbs Isaiah</filingPersonName>
				<principalBusinessOfficeOrResidenceAddress>706 Park Blvd.
Austin, TX 78751</principalBusinessOfficeOrResidenceAddress>
				<citizenship>United States</citizenship>
			</item2>
			<item3>
				<notApplicableFlag>Y</notApplicableFlag>
			</item3>
			<item4>
				<amountBeneficiallyOwned>1,830,007</amountBeneficiallyOwned>
				<classPercent>8.67</classPercent>
				<numberOfSharesPersonHas>
					<solePowerOrDirectToVote>1,830,007</solePowerOrDirectToVote>
					<sharedPowerOrDirectToVote>0</sharedPowerOrDirectToVote>
					<solePowerOrDirectToDispose>1,830,007</solePowerOrDirectToDispose>
					<sharedPowerOrDirectToDispose>0</sharedPowerOrDirectToDispose>
				</numberOfSharesPersonHas>
			</item4>
			<item5>
				<notApplicableFlag>Y</notApplicableFlag>
			</item5>
			<item6>
				<notApplicableFlag>Y</notApplicableFlag>
			</item6>
			<item7>
				<notApplicableFlag>Y</notApplicableFlag>
			</item7>
			<item8>
				<notApplicableFlag>Y</notApplicableFlag>
			</item8>
			<item9>
				<notApplicableFlag>Y</notApplicableFlag>
			</item9>
			<item10>
				<certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
			</item10>
		</items>
		<signatureInformation>
			<reportingPersonName>Tibbs Isaiah</reportingPersonName>
			<signatureDetails>
				<signature>Tibbs Isaiah</signature>
				<title>Individual</title>
				<date>03/12/2026</date>
			</signatureDetails>
		</signatureInformation>
	</formData>
</edgarSubmission>
