X0306 4 2022-12-01 1 0001744659 Akero Therapeutics, Inc. AKRO 0001869333 Skorpios Trust 195 ARCH. MAKARIOS III AVE. NEOCLEOUS HOUSE LIMASSOL G4 3030 CYPRUS 0 0 0 1 Former 10% owner 0001869057 Blue Horizon Enterprise Ltd 3076 SIR FRANCIS DRAKE'S HIGHWAY ROAD TOWN TORTOLA D8 VIRGIN ISLANDS, BRITISH 0 0 0 1 Former 10% owner 0001869027 Ezbon International Ltd 3076 SIR FRANCIS DRAKE'S HIGHWAY ROAD TOWN TORTOLA D8 VIRGIN ISLANDS, BRITISH 0 0 0 1 Former 10% owner 0001869331 Montrago Trustees Ltd 195 ARCH. MAKARIOS III AVE NEOCLEOUS HOUSE LIMASSOL G4 3030 CYPRUS 0 0 0 1 Former 10% owner Common Stock 2022-12-01 4 S 0 1636000 43.50 D 3271829 I See Footnote Blue Horizon Enterprise Ltd. ("Blue Horizon") is the direct owner of 2,346,298 shares of the issuer's common stock and Ezbon International Limited ("Ezbon") is the direct owner of 925,531 shares of the issuer's common stock. Skorpios Trust ("Skorpios") is the sole owner of each of Blue Horizon and Ezbon. Montrago Trustees Limited ("Montrago Trustees") is the corporate trustee of Skorpios Trust. Each of Blue Horizon and Ezbon disclaim beneficial ownership of the shares of the issuer's common stock held by the other, and each of Skorpios Trust and Montrago Trustees disclaim beneficial ownership of the issuer's securities except to the extent of their pecuniary interest therein. /s/ Androulla Papadopoulou, Authorized Signatory on behalf of Skorpios Trust 2022-12-05 /s/ Anna Maria Pavlou, Authorized Signatory on behalf of Blue Horizon Enterprise Ltd. 2022-12-05 /s/ Anna Maria Pavlou, Authorized Signatory on behalf of Ezbon International Limited 2022-12-05 /s/ Androulla Papadopoulou, Authorized Signatory on behalf of Montrago Trustees Limited 2022-12-05