X0306 4 2021-08-19 0 0001828673 HCW Biologics Inc. HCWB 0001866254 Flowers Lee C/O HCW BIOLOGICS INC 2929 N. COMMERCE PARKWAY MIRAMAR FL 33025 0 1 0 0 SVP of Business Development Common Stock 2021-08-19 4 P 0 10532 4.2523 A 78209 D The range of prices for the shares of Common Stock is from $4.2519 to $4.27. The reporting person undertakes that he will provide, upon request by the staff of the U.S. Securities and Exchange Commission, full information regarding the number of securities purchased at each separate price. /s/ Lee D. Flowers 2021-08-23