X0206 3 2022-05-11 0 0001865494 IO Biotech, Inc. IOBT 0001865633 Burkavage Brian C/O IO BIOTECH, INC. OLE MAALOES VEH 3 COPENHAGEN G7 2200 DENMARK true Chief Accounting Officer Common Stock 1500 D Stock Option (Right to Buy) 8.52 2032-02-15 Common Stock 53000 D One-fourth of these options vest on 10/29/2022, and 1/48th of these options vest each month thereafter, subject to the reporting person's continued service through the applicable vesting date, and subject to 50% acceleration upon a change of control. Exhibit List: Exhibit 24 - Power of Attorney /s/ Brian Burkavage 2022-05-13