Exhibit 21.1

SUBSIDIARIES OF AMEREN CORPORATION

AT DECEMBER 31, 2022

Name	State or Jurisdiction of Organization
Ameren Corporation	Missouri
Ameren Development Company	Missouri
Missouri Central Railroad Company	Delaware
QST Enterprises Inc.	Illinois
Ameren EIP Investment, LLC	Delaware
Ameren Accelerator Investments, LLC	Delaware
AmerenEnergy Medina Valley Cogen, L.L.C.	Illinois
Ameren Transmission Company, LLC	Delaware
ATX East, LLC	Delaware
ATX Southwest, LLC	Delaware
ATX-TIP Holdings, Inc.	Ontario
Lucky Corridor, LLC	Colorado
Mora Line, LLC	Colorado
Ameren Transmission Company of Illinois	Illinois
Ameren Services Company	Missouri
Ameren Illinois Company	Illinois
Union Electric Company (d/b/a Ameren Missouri)	Missouri
Ameren Missouri Renewables Holdco, LLC	Delaware
BREC Holding Company, LLC	Delaware
HFREC Holding Company, LLC	Delaware
STARS Alliance, LLC (25% interest)	Delaware

Subsidiaries not included on this list, considered in the aggregate as a single subsidiary, would not constitute a significant subsidiary as of December 31, 2022.