144 0001865125 XXXXXXXX LIVE 0001672619 Enliven Therapeutics, Inc. 001-39247 205 PARK ROAD BURLINGAME CA 94010 7206478519 Derynck Mika K Director Common Jefferies LLC

520 Madison Avenue, 4th Floor New York NY 10022

158795 9216461.80 71000000 08/04/2026 NASDAQ Common 08/09/2022 Stock Options Enliven Therapeutics N 87373 08/09/2022 N/A Common 02/23/2023 Stock Options Enliven Therapeutics N 27567 02/23/2023 N/A Common 02/13/2024 Stock Options Enliven Therapeutics N 23364 02/13/2024 N/A Common 02/06/2025 Stock Options Enliven Therapeutics N 20491 02/06/2025 N/A Y All sales are to be made pursuant to a previously signed/adopted 10b5-1 Selling Plan dated 04/08/2025, and all representations regarding material non-public information were made as of the adoption of the plan. 08/04/2026 04/08/2025 Mika Derynck