144 0001880946 XXXXXXXX LIVE 0001863127 Tyra Biosciences, Inc 001-40800 2656 State St Carlsbad CA 92008 6197284760 Daniel Bensen Officer Common Merrill Lynch

2049 Century Park E, Ste 1200 Los Angeles CA 90067

20072 320000 53372098 11/17/2025 Nasdaq Common 08/28/2018 Founders shares Issuer N 20072 08/28/2018 n/a N Daniel Bensen

2656 State St Carlsbad CA 92008

Common 11/13/2025 1111 17000 Daniel Bensen

2656 State St Carlsbad CA 92008

Common 11/14/2025 110225 1760000 11/17/2025 Daniel Bensen