X0306 4 2021-09-17 0 0001863127 Tyra Biosciences, Inc. TYRA 0001712417 Canaan XI L.P. C/O CANAAN PARTNERS 285 RIVERSIDE AVENUE, SUITE 250 WESTPORT CT 06880 0 0 1 0 0001850694 Canaan Partners XI LLC C/O CANAAN PARTNERS 285 RIVERSIDE AVENUE, SUITE 250 WESTPORT CT 06880 0 0 1 0 0001882023 Canaan 2020+ Co-Investment L.P. Series 7 C/O CANAAN PARTNERS 285 RIVERSIDE AVENUE, SUITE 250 WESTPORT CT 06880 0 0 1 0 0001881618 Canaan Partners 2020+ Co-Investment LLC C/O CANAAN PARTNERS 285 RIVERSIDE AVENUE, SUITE 250 WESTPORT CT 06880 0 0 1 0 Common Stock 2021-09-17 4 C 0 3936595 A 3936595 D Common Stock 2021-09-17 4 C 0 473396 A 473396 D Series A Preferred Stock 2021-09-17 4 C 0 1333334 0.00 D Common Stock 3463201 0 D Series B Preferred Stock 2021-09-17 4 C 0 182257 0.00 D Common Stock 473394 0 D Series B Preferred Stock 2021-09-17 4 C 0 182258 0.00 D Common Stock 473396 0 D On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date. The shares are held directly by Canaan XI L.P. ("Canaan XI"). The sole general partner of Canaan XI is Canaan Partners XI LLC ("Canaan XI GP"), which may be deemed to have sole voting, investment and dispositive power with respect to the shares held by Canaan XI. Canaan XI GP disclaims Section 16 beneficial ownership of the securities held by Canaan XI, except to the extent of its pecuniary interest therein, if any. The shares are held directly by Canaan 2020+ Co-Investment L.P. - Series 7 (the "Canaan Series 7"). The sole general partner of Canaan Series 7 is Canaan Partners 2020+ Co-Investment LLC ("Canaan 2020+ GP"), which may be deemed to have sole voting, investment and dispositive power with respect to the shares held by Canaan Series 7. Canaan 2020+ GP disclaims Section 16 beneficial ownership of the securities held by Canaan Series 7, except to the extent of its pecuniary interest therein, if any. Exhibit 24 - Power of Attorney (incorporated herein by reference to the Power of Attorney filed as Exhibit 24 to the Form 3 filed by the Reporting Persons on September 14, 2021) Canaan XI L.P., By: Canaan Partners XI LLC, its general partner, By: /s/ Nancy Levenson, Attorney-in-Fact 2021-09-20 Canaan Partners XI LLC, By: /s/ Nancy Levenson, Attorney-in-Fact 2021-09-20 Canaan 2020+ Co-Investment L.P. - Series 7, By: Canaan Partners 2020+ Co-Investment LLC, as its General Partner, By: Canaan Management LLC, its Manager, By: /s/ John J. Pacifico, Chief Operating Officer 2021-09-20 Canaan Partners 2020+ Co-Investment LLC, By: Canaan Management LLC, its Manager, By: /s/ John J. Pacifico, Chief Operating Officer 2021-09-20