X0206 3 2021-09-14 0 0001863127 Tyra Biosciences, Inc. TYRA 0001207792 MORE ROBERT J C/O TYRA BIOSCIENCES, INC. 2656 STATE STREET CARLSBAD CA 92008 1 0 1 0 Common Stock 112929 I See footnotes Series A Preferred Stock 0.00 Common Stock 3148365 I See footnotes Series B Preferred Stock 0.00 Common Stock 662752 I See footnotes These securities are held directly by Alta Partners NextGen Fund II, L.P. (the "APNG II"). The Reporting Person is a managing director of the general partner of APNG II and shares voting and investment control with respect to the shares held by APNG II. The Reporting Person disclaims beneficial ownership of all shares held by APNG II, except to the extent of his pecuniary interest therein. The shares of Series A Preferred Stock and Series B Preferred Stock are convertible, at any time, at the holder's election, to shares of the Issuer's common stock at a ratio of 1-for-2.5974. In addition, effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of Series A Preferred Stock and Series B Preferred Stock will automatically convert to shares of the Issuer's common stock at a ratio of 1-for-2.5974. The Series A Preferred Stock and Series B Preferred Stock has no expiration date. Exhibit List: Exhibit 24 - Power of Attorney /s/ John Healy, Attorney-in Fact 2021-09-14