X0508 4 2024-11-29 0001861560 Nuvalent, Inc. NUVL 0001862147 Balcom Alexandra C/O NUVALENT, INC. ONE BROADWAY, 14TH FLOOR CAMBRIDGE MA 02142 false true false false Chief Financial Officer true Class A Common Stock 2024-11-29 4 M false 10000 27.85 A 43300 D Class A Common Stock 2024-11-29 4 S false 8142 95.69 D 35158 D Class A Common Stock 2024-11-29 4 S false 1858 96.25 D 33300 D Stock Option (Right to Buy) 27.85 2024-11-29 4 M false 10000 0 D 2033-01-06 Class A Common Stock 10000 84200 D These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 28, 2023. The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $95.06 to $96.05, inclusive. The reporting person undertakes to provide to the staff of the Securities and Exchange Commission, Nuvalent, Inc. or any security holder of Nuvalent, Inc., upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2) and (3) of this Form 4. The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $96.06 to $96.78, inclusive. The shares underlying this option have vested or shall vest over the four years following January 6, 2023 in equal monthly installments, subject to continued service to Nuvalent, Inc. through the applicable vesting date. /s/ Nathan McConarty, attorney-in-fact 2024-12-03