CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022
Cash flows from operating activities:
Net loss	$ (126,219)	$ (81,854)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation expense	25,563	10,325
Net accretion of discounts on marketable securities	(10,109)	(373)
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	644	(1,491)
Other assets	(1,428)	(1,272)
Accounts payable	2,169	4,212
Accrued expenses	9,641	5,482
Net cash used in operating activities	(99,739)	(64,971)
Cash flows from investing activities:
Purchases of marketable securities	(459,486)	(212,916)
Proceeds from sales and maturities of marketable securities	315,959	202,251
Net cash used in investing activities	(143,527)	(10,665)
Cash flows from financing activities:
Proceeds from public offerings, net of underwriting discounts and commissions	324,300	248,630
Proceeds from exercise of stock options	13,793	1,840
Proceeds from issuance of common stock under employee stock purchase plan	387
Payments of public offering costs	(856)	(644)
Payments of insurance costs financed by a third-party	(777)	(910)
Net cash provided by financing activities	336,847	248,916
Net increase in cash and cash equivalents	93,581	173,280
Cash and cash equivalents at beginning of period	241,806	68,526
Cash and cash equivalents at end of period	335,387	241,806
Supplemental disclosure of noncash financing information:
Insurance premium financed by a third-party	$ 1,399	1,820
Public offering costs included in accounts payable		$ 90