X0206 3 2021-07-28 0 0001861560 Nuvalent, Inc. NUVL 0001862148 Noci Darlene C/O NUVALENT, INC. ONE BROADWAY, 14TH FLOOR CAMBRIDGE MA 02142 0 1 0 0 See Remarks Stock Option (Right to Buy) 1.08 2031-02-15 Class A Common Stock 170589 D Stock Option (Right to Buy) 6.89 2031-04-29 Class A Common Stock 41764 D The shares underlying this option vest as follows: 25% of the shares vested on January 11, 2022 and the remainder vest over the next three years in equal monthly installments, subject to continued service to the Company through the applicable vesting date. The shares underlying this option vest as follows: 25% of the shares vested on April 29, 2022 and the remainder vest over the next three years in equal monthly installments, subject to continued service to the Company through the applicable vesting date. SVP of Product Development & Regulatory Affairs Exhibit 24: Power of Attorney /s/ Alexandra Balcom, attorney-in-fact 2021-07-28