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Note 6 - Stockholders' Equity (Tables)
9 Months Ended
Sep. 30, 2025
Notes Tables  
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
  

Three Months Ended

  

Nine Months Ended

 
  

September 30,

  

September 30,

 

($ in thousands)

 

2025

  

2024

  

2025

  

2024

 

Research and development

 $76  $11  $217  $8 

General and administrative

  56   6   218   (1)

Total stock-based compensation expense

 $132  $17  $435  $7 
Schedule of Nonvested Restricted Stock Units Activity [Table Text Block]
      

Weighted

 
  

Number of

  

Average Grant

 
  Units  Date Fair Value 

Unvested balance at December 31, 2024

  174,038  $2.36 

Granted

  570,671  $1.01 

Vested

  (39,494) $2.11 

Forfeited

  (85,051) $2.23 

Unvested balance at September 30, 2025

  620,164  $1.15 
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
          

Weighted

     
          

Average

     
      

Weighted

  

Remaining

  

Aggregate

 
  

Number

  

Average

  

Contractual

  

Intrinsic Value

 
  

of Options

  

Exercise Price

  

Term (years)

  

(in thousands)

 

Outstanding at December 31, 2024

    $     $ 

Issued

  75,000   1.01   9.3    

Forfeited

  (25,000)  1.01   9.3    

Outstanding at September 30, 2025

  50,000  $1.01   9.3  $ 

Exercisable

    $     $ 
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
    
  

As of September 30,

 
  

2025

  

2024

 

Volatility

  135%   

Expected term (in years)

  

5.6

    

Risk-free rate

  3.7%   

Expected dividend yield