X0206 3 2021-07-29 0 0001858848 Tenaya Therapeutics, Inc. TNYA 0001642996 CHEN JIN-LONG C/O TENAYA THERAPEUTICS, INC. 171 OYSTER POINT BLVD., 5TH FLR SOUTH SAN FRANCISCO CA 94080 1 0 0 0 Common Stock 25000 D Stock Option (Right to Buy) 2.70 2029-12-06 Common Stock 5000 D 1/12th of the shares subject to the option granted on December 6, 2019 became vested and exercisable as of November 1, 2019 and 1/12th of the shares subject to the option shall vest monthly thereafter, provided that the Reporting Person remains a service provider to the issuer on each such vest date. Date set forth above represents the effective date of the Issuer's initial public offering. /s/ Leone Patterson Attorney-in-Fact for Jin-Long Chen 2021-07-29