144 0001668159 XXXXXXXX LIVE 0001858848 Tenaya Therapeutics, Inc. 001-40656 171 OYSTER POINT BLVD., SUITE 500 SOUTH SAN FRANCISCO CA 94080 415-865-2066 COLUMN GROUP III, LP 10% Stockholder Common BTIG, LLC

350 Bush Street 9th Floor San Francisco CA 94104

1408910 872537.96 213744535 02/20/2026 NASDAQ GS Common 07/31/2017 Series A financing Tenaya Therapeutics N 200028 07/31/2017 Cash Common 12/20/2018 Series A financing Tenaya Therapeutics N 1208882 12/20/2018 Cash N COLUMN GROUP III, LP

1 Letterman Drive Suite DM-900 San Francisco CA 94129

Common 02/10/2026 161422 131736.49 COLUMN GROUP III, LP

1 Letterman Drive, Suite DM-900 San Francisco CA 94129

Common 02/11/2026 1905115 1297002.29 02/20/2026 James Evangelista