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Condensed Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Cash flows from operating activities:    
Net loss $ (50,147) $ (61,659)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 4,745 4,278
Amortization (accretion) of premium (discount) on marketable securities 300 68
Stock-based compensation 7,367 8,835
Non-cash operating lease expense 1,208 1,625
Other 230 154
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets 1,488 1,138
Other noncurrent assets 508 351
Accounts payable (1,514) (1,160)
Accrued and other current liabilities (1,512) (3,754)
Operating lease liabilities (1,398) (2,153)
Net cash used in operating activities (38,725) (52,277)
Cash flows from investing activities:    
Purchases of property and equipment (525) (637)
Purchases of marketable securities   (34,451)
Proceeds from sales of marketable securities 10,958  
Proceeds from maturities of marketable securities 36,857 52,209
Other 0 5
Net cash provided by investing activities 47,290 17,126
Cash flows from financing activities:    
Proceeds from exercise of stock options and employee stock purchase plan 70 578
Proceeds from exercise of prefunded warrants   1
Net cash provided by financing activities 49,783 47,341
Net change in cash, cash equivalents and restricted cash 58,348 12,190
Cash and cash equivalents and restricted cash at beginning of period 4,742 46,363
Cash and cash equivalents and restricted cash at end of period 63,090 58,553
Components of cash, cash equivalents and restricted cash:    
Cash and cash equivalents 62,671 58,134
Restricted cash included in other noncurrent assets 419 419
Cash, cash equivalents and restricted cash 63,090 58,553
Supplemental disclosure of non-cash investing and financing activities:    
Property and equipment included in accounts payable and accrued and other current liabilities 7 98
Follow-on Offering    
Cash flows from financing activities:    
Proceeds from issuance of equity, net of issuance costs 48,801 46,762
At-the-market Sales    
Cash flows from financing activities:    
Proceeds from issuance of equity, net of issuance costs $ 912 $ 0