Condensed Statements of Cash Flows (Unaudited) $ in Thousands	6 Months Ended
	Jun. 30, 2024 USD ($)	Jun. 30, 2023 USD ($)
Cash flows from operating activities:
Net loss	$ (61,659)	$ (65,006)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	4,278	4,325
Amortization (accretion) of premium (discount) on marketable securities	68	(1,056)
Stock-based compensation	8,835	7,345
Non-cash operating lease expense	1,625	1,530
Other	154	105
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	1,138	733
Other noncurrent assets	351	(726)
Accounts payable	(1,160)	(223)
Accrued and other current liabilities	(3,754)	(1,542)
Operating lease liabilities	(2,153)	(1,995)
Net cash used in operating activities	(52,277)	(56,510)
Cash flows from investing activities:
Purchases of property and equipment	(637)	(837)
Purchases of marketable securities	(34,451)	(40,998)
Proceeds from maturities of marketable securities	52,209	74,984
Other	5	(3)
Net cash provided by investing activities	17,126	33,146
Cash flows from financing activities:
Proceeds from issuance of common stock and pre-funded warrants in follow-on offering, net of issuance costs	46,762
Proceeds from exercise of stock options and employee stock purchase plan	578	311
Proceeds from exercises of pre-funded warrants	1
Proceeds from at-the-market sales, net of issuance costs	0	3,868
Payment of accrued offering costs	0	(501)
Net cash provided by financing activities	47,341	3,678
Net change in cash, cash equivalents and restricted cash	12,190	(19,686)
Cash and cash equivalents and restricted cash at beginning of period	46,363	95,671
Cash and cash equivalents and restricted cash at end of period	58,553	75,985
Components of cash, cash equivalents and restricted cash:
Cash and cash equivalents	58,134	75,565
Restricted cash included in other noncurrent assets	419	420
Cash, cash equivalents and restricted cash	58,553	75,985
Supplemental disclosure of non-cash investing and financing activities:
Property and equipment included in accounts payable and accrued and other current liabilities	$ 98	$ 44