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Condensed Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2024
Mar. 31, 2023
Cash flows from operating activities:    
Net loss $ (32,228) $ (31,737)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 2,155 2,130
Amortization (accretion) of premium (discount) on marketable securities (74) (567)
Stock-based compensation 4,224 3,514
Non-cash operating lease expense 802 754
Other 100 52
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets 447 366
Other noncurrent assets 50 163
Accounts payable 1,272 (1,324)
Accrued and other current liabilities (4,350) (2,662)
Operating lease liabilities (1,058) (979)
Net cash used in operating activities (28,660) (30,290)
Cash flows from investing activities:    
Purchases of property and equipment (564) (629)
Purchases of marketable securities (23,643) (25,798)
Proceeds from maturities of marketable securities 19,717 34,500
Other 1 (12)
Net cash (used in) provided by investing activities (4,489) 8,061
Cash flows from financing activities:    
Proceeds from issuance of common stock and pre-funded warrants in follow-on offering, net of issuance costs 46,762  
Proceeds from exercise of stock options and employee stock purchase plan 8  
Proceeds from exercises of pre-funded warrants 1  
Payment of accrued offering costs 0 (501)
Net cash provided by (used in) financing activities 46,771 (501)
Net change in cash, cash equivalents and restricted cash 13,622 (22,730)
Cash and cash equivalents and restricted cash at beginning of period 46,363 95,671
Cash and cash equivalents and restricted cash at end of period 59,985 72,941
Components of cash, cash equivalents and restricted cash:    
Cash and cash equivalents 59,303 72,542
Restricted cash included in other noncurrent assets 682 399
Cash, cash equivalents and restricted cash 59,985 72,941
Supplemental disclosure of non-cash investing and financing activities:    
Property and equipment included in accounts payable and accrued and other current liabilities 7 $ 370
Non-cash exercise of stock options $ 3