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Condensed Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Cash flows from operating activities:    
Net loss $ (31,056) $ (13,098)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 966 689
Amortization of premium on marketable securities 143  
Stock-based compensation 2,094 432
Non-cash operating lease expense 332 171
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets 732 118
Other noncurrent assets 25 (3,313)
Accounts payable (1,779) 618
Accrued expenses and other current liabilities 318 (1,022)
Operating lease liabilities (533) (384)
Other noncurrent liabilities 2  
Net cash used in operating activities (28,756) (15,789)
Cash flows from investing activities:    
Purchases of property and equipment (8,595) (4,323)
Purchases of marketable securities (43,171)  
Proceeds from maturities of marketable securities 68,200  
Net cash provided by (used in) investing activities 16,434 (4,323)
Cash flows from financing activities:    
Proceeds from exercise of stock options 15 29
Net cash provided by financing activities 15 20,015
Net change in cash, cash equivalents and restricted cash (12,307) (97)
Cash and cash equivalents and restricted cash at beginning of period 38,676 129,083
Cash and cash equivalents and restricted cash at end of period 26,369 128,986
Components of cash, cash equivalents and restricted cash:    
Cash and cash equivalents 25,970 128,439
Restricted cash, noncurrent 399 547
Cash, cash equivalents and restricted cash 26,369 128,986
Supplemental disclosure of cash operating activities:    
Cash paid for leases included in operating cash outflows 1,366 1,389
Supplemental disclosure of non-cash operating activities:    
Lease liability obtained in exchange for right-of-use asset   213
Supplemental disclosure of non-cash investing and financing activities:    
Deferred offering costs related to initial public offering included in accounts payable   74
Property and equipment included in accounts payable and accrued expenses and other current liabilities $ 5,282 452
Series C Convertible Preferred Stock    
Cash flows from financing activities:    
Proceeds from issuance of convertible preferred stock, net of issuance costs   $ 19,986