X0206 3 2021-07-29 0 0001850838 Omega Therapeutics, Inc. OMGA 0001858760 McCauley Thomas C/O OMEGA THERAPEUTICS, INC. 20 ACORN PARK DRIVE CAMBRIDGE MA 02140 0 1 0 0 Chief Scientific Officer Common Stock 21176 D Stock Option (Right to Buy) 0.60 2029-09-16 Common Stock 273720 D Stock Option (Right to Buy) 5.67 2031-03-28 Common Stock 186617 D The options vest and become exercisable with respect to 25% of the underlying shares on July 29, 2020 and in equal quarterly installments thereafter such that the option will become fully vested and exercisable on July 29, 2023, subject to the Reporting Person's continued service to the Issuer through each vesting date. The options vest and become exercisable with respect to 25% of the underlying shares on March 26, 2022 and in equal quarterly installments thereafter such that the option will become fully vested and exercisable on March 26, 2025, subject to the Reporting Person's continued service to the Issuer through each vesting date. Exhibit 24 - Power of Attorney. /s/ Barbara Chan as Attorney-in-fact for Thomas McCauley, Ph.D. 2021-07-29