Exhibit 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We hereby consent to the inclusion in this Registration Statement of Prime Number Acquisition I Corp. (the “Company”) on Form S-1 of our report dated February 1, 2022, with respect to our audit of the Company’s financial statements as of December 31, 2021, and for the period from February 25, 2021 (inception) through December 31, 2021, which appears in this Registration Statement on Form S-1. Our report contained an explanatory paragraph regarding uncertainty about the Company’s ability to continue as a going concern.

We also consent to the reference to our Firm under the caption “Experts” in such Prospectus.

/s/ UHY LLP

New York, New York

February 1, 2022