Accrued Expenses - Schedule of Accrued Expenses (Details) - USD ($) $ in Thousands	3 Months Ended	12 Months Ended
	Mar. 31, 2022	Dec. 31, 2021
Accrued Liabilities [Abstract]
Payroll and related	$ 1,250	$ 202
Accrued preclinical and clinical trial costs	389	621
Accrued professional fees	323	213
Other	139	398
Total accrued expenses	$ 2,101	$ 1,434