The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACLARIS THERAPEUTICS INC COM 00461U105   35,043,750 9,345,000 SH   SOLE   9,345,000 0 0
ALIGOS THERAPEUTICS INC COM NEW 01626L204   3,299,737 444,110 SH   SOLE   444,110 0 0
ALKERMES PLC SHS G01767105   126,953,821 3,590,323 SH   SOLE   3,590,323 0 0
ALUMIS INC COM 022307102   149,200,268 6,772,595 SH   SOLE   6,772,595 0 0
ANI PHARMACEUTICALS INC COM 00182C103   46,140,000 600,000 SH   SOLE   600,000 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   182,337,406 4,532,374 SH   SOLE   4,532,374 0 0
APOGEE THERAPEUTICS INC COM 03770N101   23,988,450 285,000 SH   SOLE   285,000 0 0
ATAIBECKLEY INC COM SHS 04650F101   42,480,000 12,000,000 SH   SOLE   12,000,000 0 0
AXSOME THERAPEUTICS INC. COM 05464T104   185,922,000 1,100,000 SH   SOLE   1,100,000 0 0
BEAM THERAPEUTICS INC COM 07373V105   19,558,830 820,765 SH   SOLE   820,765 0 0
BICARA THERAPEUTICS INC COM 055477103   80,803,125 4,062,500 SH   SOLE   4,062,500 0 0
BILLIONTOONE INC CL A 090168105   3,947,000 50,000 SH   SOLE   50,000 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101   64,963,500 1,150,000 SH   SOLE   1,150,000 0 0
BRIDGEBIO PHARMA INC COM 10806X102   62,485,706 841,445 SH   SOLE   841,445 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202   40,727,814 1,283,979 SH   SOLE   1,283,979 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100   125,437,389 3,158,041 SH   SOLE   3,158,041 0 0
CENTURY THERAPEUTICS INC COM 15673T100   21,442,304 9,487,745 SH   SOLE   9,487,745 0 0
COGENT BIOSCIENCES INC COM 19240Q201   38,490,000 1,000,000 SH   SOLE   1,000,000 0 0
COMPASS PATHWAYS PLC SPONSORED ADS 20451W101   67,253,073 12,161,496 SH   SOLE   12,161,496 0 0
CONTEXT THERAPEUTICS INC COM 21077P108   19,438,710 7,419,355 SH   SOLE   7,419,355 0 0
CORMEDIX INC COM 21900C308   42,600,976 6,274,076 SH   SOLE   6,274,076 0 0
CORVUS PHARMACEUTICALS INC COM 221015100   36,451,216 2,491,539 SH   SOLE   2,491,539 0 0
CRESCENT BIOPHARMA INC. COM G2545C104   8,334,212 453,686 SH   SOLE   453,686 0 0
CYBIN INC COM NEW 23256X407   6,303,058 1,313,137 SH   SOLE   1,313,137 0 0
CYTOKINETICS INC COM NEW 23282W605   90,581,431 1,374,320 SH   SOLE   1,374,320 0 0
DEFINIUM THERAPEUTICS INC COM SHS 24477V105   56,700,000 3,000,000 SH   SOLE   3,000,000 0 0
DYNE THERAPEUTICS INC COM 26818M108   36,260,000 2,000,000 SH   SOLE   2,000,000 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106   24,715,230 1,956,867 SH   SOLE   1,956,867 0 0
ENGENE HOLDINGS INC COM 29286M105   29,811,265 4,377,572 SH   SOLE   4,377,572 0 0
GENMAB A/S SPONSORED ADS 372303206   98,284,998 3,663,250 SH   SOLE   3,663,250 0 0
GERON CORP COM 374163103   47,263,214 31,720,278 SH   SOLE   31,720,278 0 0
GRAIL INC COM 384747101   89,034,149 1,722,797 SH   SOLE   1,722,797 0 0
GUARDANT HEALTH INC COM 40131M109   308,353,321 3,338,241 SH   SOLE   3,338,241 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105   58,246,303 1,931,884 SH   SOLE   1,931,884 0 0
IMMUNOVANT INC COM 45258J102   286,329,960 11,526,971 SH   SOLE   11,526,971 0 0
INVENTIVA SA ADS 46124U107   6,784,614 1,222,453 SH   SOLE   1,222,453 0 0
IONIS PHARMACEUTICALS INC COM 462222100   146,425,500 1,950,000 SH   SOLE   1,950,000 0 0
JANUX THERAPEUTICS INC COM 47103J105   16,503,331 1,187,290 SH   SOLE   1,187,290 0 0
KURA ONCOLOGY INC COM 50127T109   21,491,996 2,643,542 SH   SOLE   2,643,542 0 0
LARIMAR THERAPEUTICS INC COM 517125100   6,750,000 1,500,000 SH   SOLE   1,500,000 0 0
LB PHARMACEUTICALS INC COM SHS 50180M108   82,680,147 3,352,804 SH   SOLE   3,352,804 0 0
MAZE THERAPEUTICS INC COM 578784100   103,805,226 3,477,562 SH   SOLE   3,477,562 0 0
MBX BIOSCIENCES INC COM 55287L101   82,313,435 2,757,569 SH   SOLE   2,757,569 0 0
MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104   119,461,206 6,408,863 SH   SOLE   6,408,863 0 0
NURIX THERAPEUTICS INC COM 67080M103   98,351,282 6,345,244 SH   SOLE   6,345,244 0 0
NUVALENT INC COM 670703107   141,004,394 1,376,324 SH   SOLE   1,376,324 0 0
OCULAR THERAPEUTIX INC COM 67576A100   166,742,809 19,686,282 SH   SOLE   19,686,282 0 0
ORUKA THERAPEUTICS INC COM 687604108   99,777,657 2,034,203 SH   SOLE   2,034,203 0 0
PERSONALIS INC COM 71535D106   19,110,000 3,000,000 SH   SOLE   3,000,000 0 0
PROMIS NEUROSCIENCES INC COM SHS 74346M505   10,612,819 835,655 SH   SOLE   835,655 0 0
SOLENO THERAPEUTICS INC COM 834203309   36,115,211 1,078,710 SH   SOLE   1,078,710 0 0
SOLID BIOSCIENCES INC COM NEW 83422E204   25,668,446 3,565,062 SH   SOLE   3,565,062 0 0
SPDR SERIES TRUST STATE STREET SPD 78464A870   1,277,300,000 10,000,000 SH Put SOLE   10,000,000 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106   206,288,674 4,279,848 SH   SOLE   4,279,848 0 0
TANGO THERAPEUTICS INC COM 87583X109   57,530,000 2,750,000 SH   SOLE   2,750,000 0 0
TARSUS PHARMACEUTICALS INC COM 87650L103   252,540,000 3,600,000 SH   SOLE   3,600,000 0 0
TERNS PHARMACEUTICALS INC COM 880881107   56,614,795 1,073,877 SH   SOLE   1,073,877 0 0
VAXCYTE INC COM 92243G108   249,873,000 4,300,000 SH   SOLE   4,300,000 0 0
VERA THERAPEUTICS INC CL A 92337R101   165,187,075 4,106,067 SH   SOLE   4,106,067 0 0
VERADERMICS INC COMMON STOCK 922967104   31,575,000 500,000 SH   SOLE   500,000 0 0
VERASTEM INC COM NEW 92337C203   30,426,505 5,740,850 SH   SOLE   5,740,850 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   27,265,545 1,393,944 SH   SOLE   1,393,944 0 0
X4 PHARMACEUTICALS INC COM NEW 98420X202   26,182,280 6,339,535 SH   SOLE   6,339,535 0 0