The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
4D MOLECULAR THERAPEUTICS IN COM 35104E100   46,281,377 2,284,372 SH   SOLE   2,284,372 0 0
ABIVAX SA SPONSORED ADS 00370M103   45,982,587 4,297,438 SH   SOLE   4,297,438 0 0
AGENUS INC COM NEW 00847G705   26,242,393 31,697,539 SH   SOLE   31,697,539 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104   23,670,360 1,062,881 SH   SOLE   1,062,881 0 0
ALKERMES PLC SHS G01767105   110,960,000 4,000,000 SH   SOLE   4,000,000 0 0
ALLAKOS INC COM 01671P100   6,854,309 2,510,736 SH   SOLE   2,510,736 0 0
ALIGOS THERAPEUTICS INC COM 01626L105   4,052,239 6,102,770 SH   SOLE   6,102,770 0 0
AMBRX BIOPHARMA INC COM 641871108   52,836,267 3,710,412 SH   SOLE   3,710,412 0 0
ANAPTYSBIO INC COM 032724106   43,632,326 2,036,990 SH   SOLE   2,036,990 0 0
ANI PHARMACEUTICALS INC COM 00182C103   33,084,000 600,000 SH   SOLE   600,000 0 0
APOGEE THERAPEUTICS INC COM 03770N101   64,917,361 2,323,456 SH   SOLE   2,323,456 0 0
ARCELLX INC COMMON STOCK 03940C100   40,245,548 725,145 SH   SOLE   725,145 0 0
ARGENX SE SPONSORED ADR 04016X101   114,129,000 300,000 SH   SOLE   300,000 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100   76,438,273 11,869,297 SH   SOLE   11,869,297 0 0
AXSOME THERAPEUTICS INC COM 05464T104   79,590,000 1,000,000 SH   SOLE   1,000,000 0 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108   63,108,348 3,490,506 SH   SOLE   3,490,506 0 0
CYTOKINETICS INC COM NEW 23282W605   24,124,352 288,949 SH   SOLE   288,949 0 0
CYTOKINETICS INC COM NEW 23282W605   112,486,077 1,347,300 SH Call SOLE   1,347,300 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201   99,163,132 7,093,214 SH   SOLE   7,093,214 0 0
DYNE THERAPEUTICS INC COM 26818M108   26,600,000 2,000,000 SH   SOLE   2,000,000 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105   27,756,705 2,537,176 SH   SOLE   2,537,176 0 0
EDITAS MEDICINE INC COM 28106W103   55,442,361 5,473,086 SH   SOLE   5,473,086 0 0
GERON CORP COM 374163103   62,421,077 29,583,449 SH   SOLE   29,583,449 0 0
GH RESEARCH PLC ORDINARY SHARES G3855L106   2,896,520 499,400 SH   SOLE   499,400 0 0
GUARDANT HEALTH INC COM 40131M109   135,250,000 5,000,000 SH   SOLE   5,000,000 0 0
HILLEVAX INC COM 43157M102   46,545,000 2,900,000 SH   SOLE   2,900,000 0 0
IMMUNOVANT INC COM 45258J102   42,130,000 1,000,000 SH   SOLE   1,000,000 0 0
INSMED INC COM PAR $.01 457669307   165,796,500 5,350,000 SH   SOLE   5,350,000 0 0
INTELLIA THERAPEUTICS INC COM 45826J105   68,602,500 2,250,000 SH   SOLE   2,250,000 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101   143,240,000 2,000,000 SH   SOLE   2,000,000 0 0
IONIS PHARMACEUTICALS INC COM 462222100   63,190,350 1,249,068 SH   SOLE   1,249,068 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105   5,938,440 48,280 SH   SOLE   48,280 0 0
NEKTAR THERAPEUTICS COM 640268108   10,396,000 18,400,000 SH   SOLE   18,400,000 0 0
NURIX THERAPEUTICS INC COM 67080M103   30,937,606 2,997,830 SH   SOLE   2,997,830 0 0
NUVALENT INC COM 670703107   33,115,500 450,000 SH   SOLE   450,000 0 0
OLEMA PHARMACEUTICALS INC COM 68062P106   27,090,443 1,930,894 SH   SOLE   1,930,894 0 0
ORCHARD THERAPEUTICS PLC SPON ADS NEW 68570P200   33,585,472 2,041,670 SH   SOLE   2,041,670 0 0
OCULAR THERAPEUTIX INC COM 67576A100   41,169,230 9,230,769 SH   SOLE   9,230,769 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108   68,670,000 7,000,000 SH   SOLE   7,000,000 0 0
PLIANT THERAPEUTICS INC COM 729139105   104,132,500 5,750,000 SH   SOLE   5,750,000 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102   6,310,359 275,201 SH   SOLE   275,201 0 0
PROTHENA CORP PLC SHS G72800108   9,085,000 250,000 SH Put SOLE   250,000 0 0
PROTHENA CORP PLC SHS G72800108   18,170,000 500,000 SH Call SOLE   500,000 0 0
RAPT THERAPEUTICS INC COM 75382E109   44,580,055 1,793,966 SH   SOLE   1,793,966 0 0
RELMADA THERAPEUTICS INC COM 75955J402   8,464,259 2,044,507 SH   SOLE   2,044,507 0 0
REPARE THERAPEUTICS INC COM 760273102   21,846,936 2,992,731 SH   SOLE   2,992,731 0 0
SAREPTA THERAPEUTICS INC COM 803607100   48,215,000 500,000 SH   SOLE   500,000 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103   19,022,385 1,011,829 SH   SOLE   1,011,829 0 0
SILENCE THERAPEUTICS PLC ADS 82686Q101   33,898,945 1,951,580 SH   SOLE   1,951,580 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107   148,324,174 4,063,676 SH   SOLE   4,063,676 0 0
SPYRE THERAPEUTICS INC COM NEW 00773J202   42,023,395 1,952,760 SH   SOLE   1,952,760 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106   12,228,000 300,000 SH   SOLE   300,000 0 0
SYROS PHARMACEUTICALS INC COM NEW 87184Q206   6,453,898 828,485 SH   SOLE   828,485 0 0
TERNS PHARMACEUTICALS INC COM 880881107   39,589,000 6,100,000 SH   SOLE   6,100,000 0 0
TOURMALINE BIO INC COM 89157D105   47,539,058 1,815,854 SH   SOLE   1,815,854 0 0
TRAVERE THERAPEUTICS INC COM 89422G107   66,256,300 7,370,000 SH   SOLE   7,370,000 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106   63,365,810 3,187,415 SH   SOLE   3,187,415 0 0
VIGIL NEUROSCIENCE INC COM 92673K108   5,390,867 1,594,931 SH   SOLE   1,594,931 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   79,099,036 3,631,728 SH   SOLE   3,631,728 0 0
ZURA BIO LTD CLASS A ORD SHS G9TY5A101   11,782,410 2,523,000 SH   SOLE   2,523,000 0 0