The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X GENOMICS INC CL A COM 88025U109   7,536,004 182,691 SH   SOLE   182,691 0 0
4D MOLECULAR THERAPEUTICS IN COM 35104E100   35,365,302 2,778,107 SH   SOLE   2,778,107 0 0
89BIO INC COM 282559103   1,406,244 91,078 SH   SOLE   91,078 0 0
ACELYRIN INC COM 00445A100   5,606,609 551,289 SH   SOLE   551,289 0 0
ACUMEN PHARMACEUTICALS INC COM 00509G209   10,429,133 2,513,044 SH   SOLE   2,513,044 0 0
AGENUS INC COM NEW 00847G705   35,818,219 31,697,539 SH   SOLE   31,697,539 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104   10,450,613 422,247 SH   SOLE   422,247 0 0
ALKERMES PLC SHS G01767105   106,438,000 3,800,000 SH   SOLE   3,800,000 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101   23,058,424 1,259,335 SH   SOLE   1,259,335 0 0
ANAPTYSBIO INC COM 032724106   24,170,801 1,345,813 SH   SOLE   1,345,813 0 0
ANI PHARMACEUTICALS INC COM 00182C103   23,224,000 400,000 SH   SOLE   400,000 0 0
APOGEE THERAPEUTICS INC COM 03770N101   51,426,145 2,414,373 SH   SOLE   2,414,373 0 0
ASTRIA THERAPEUTICS INC COM 04635X102   7,742,533 1,037,873 SH   SOLE   1,037,873 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100   34,950,000 15,000,000 SH   SOLE   15,000,000 0 0
AXSOME THERAPEUTICS INC COM 05464T104   79,726,668 1,140,745 SH   SOLE   1,140,745 0 0
BEAM THERAPEUTICS INC COM 07373V105   24,426,166 1,015,641 SH   SOLE   1,015,641 0 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108   70,124,266 3,490,506 SH   SOLE   3,490,506 0 0
BIONTECH SE SPONSORED ADS 09075V102   21,728,000 200,000 SH   SOLE   200,000 0 0
CENTURY THERAPEUTICS INC COM 15673T100   1,086,016 543,008 SH   SOLE   543,008 0 0
COMPASS PATHWAYS PLC SPONSORED ADS 20451W101   2,430,338 328,424 SH   SOLE   328,424 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201   99,800,240 6,756,956 SH   SOLE   6,756,956 0 0
DYNE THERAPEUTICS INC COM 26818M108   21,536,901 2,403,672 SH   SOLE   2,403,672 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105   15,757,500 2,750,000 SH   SOLE   2,750,000 0 0
EDITAS MEDICINE INC COM 28106W103   55,395,093 7,101,935 SH   SOLE   7,101,935 0 0
GERON CORP COM 374163103   54,484,000 25,700,000 SH   SOLE   25,700,000 0 0
GH RESEARCH PLC ORDINARY SHARES G3855L106   5,018,970 499,400 SH   SOLE   499,400 0 0
GUARDANT HEALTH INC COM 40131M109   120,042,000 4,050,000 SH   SOLE   4,050,000 0 0
HERON THERAPEUTICS INC COM 427746102   2,149,305 2,086,704 SH   SOLE   2,086,704 0 0
HILLEVAX INC COM 43157M102   39,005,000 2,900,000 SH   SOLE   2,900,000 0 0
IMMUNOVANT INC COM 45258J102   107,413,492 2,797,955 SH   SOLE   2,797,955 0 0
INSMED INC COM PAR $.01 457669307   151,500,000 6,000,000 SH   SOLE   6,000,000 0 0
INTELLIA THERAPEUTICS INC COM 45826J105   63,240,000 2,000,000 SH   SOLE   2,000,000 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101   135,434,000 2,600,000 SH   SOLE   2,600,000 0 0
IONIS PHARMACEUTICALS INC COM 462222100   128,553,370 2,834,069 SH   SOLE   2,834,069 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105   147,308,545 1,138,045 SH   SOLE   1,138,045 0 0
MODERNA INC COM 60770K107   20,658,000 200,000 SH   SOLE   200,000 0 0
MORPHIC HLDG INC COM 61775R105   10,782,523 470,647 SH   SOLE   470,647 0 0
NEKTAR THERAPEUTICS COM 640268108   10,959,040 18,400,000 SH   SOLE   18,400,000 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109   33,750,000 300,000 SH   SOLE   300,000 0 0
NOVAVAX INC COM NEW 670002401   7,240,000 1,000,000 SH   SOLE   1,000,000 0 0
NOVOCURE LTD ORD SHS G6674U108   40,375,000 2,500,000 SH   SOLE   2,500,000 0 0
NURIX THERAPEUTICS INC COM 67080M103   23,562,944 2,997,830 SH   SOLE   2,997,830 0 0
NUVATION BIO INC COM CL A 67080N101   10,345,722 7,720,688 SH   SOLE   7,720,688 0 0
OLEMA PHARMACEUTICALS INC COM 68062P106   23,846,541 1,930,894 SH   SOLE   1,930,894 0 0
ORCHARD THERAPEUTICS PLC SPON ADS NEW 68570P200   15,782,109 2,041,670 SH   SOLE   2,041,670 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108   50,100,000 6,000,000 SH   SOLE   6,000,000 0 0
PLIANT THERAPEUTICS INC COM 729139105   95,370,000 5,500,000 SH   SOLE   5,500,000 0 0
POINT BIOPHARMA GLOBAL INC COM 730541109   18,553,039 2,781,565 SH   SOLE   2,781,565 0 0
PROTHENA CORP PLC SHS G72800108   12,062,500 250,000 SH Put SOLE   250,000 0 0
RAPT THERAPEUTICS INC COM 75382E109   24,930,000 1,500,000 SH   SOLE   1,500,000 0 0
RELMADA THERAPEUTICS INC COM 75955J402   8,513,454 2,837,818 SH   SOLE   2,837,818 0 0
REPARE THERAPEUTICS INC COM 760273102   37,058,190 3,067,731 SH   SOLE   3,067,731 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103   2,512,371 353,855 SH   SOLE   353,855 0 0
SILENCE THERAPEUTICS PLC ADS 82686Q101   19,164,516 1,951,580 SH   SOLE   1,951,580 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107   81,993,577 3,546,435 SH   SOLE   3,546,435 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106   96,554,300 1,915,000 SH   SOLE   1,915,000 0 0
SYROS PHARMACEUTICALS INC COM NEW 87184Q206   3,272,516 828,485 SH   SOLE   828,485 0 0
TERNS PHARMACEUTICALS INC COM 880881107   30,180,000 6,000,000 SH   SOLE   6,000,000 0 0
TRAVERE THERAPEUTICS INC COM 89422G107   65,887,800 7,370,000 SH   SOLE   7,370,000 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106   51,954,865 3,187,415 SH   SOLE   3,187,415 0 0
VIGIL NEUROSCIENCE INC COM 92673K108   9,524,836 1,767,131 SH   SOLE   1,767,131 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   45,456,516 2,963,267 SH   SOLE   2,963,267 0 0
ZURA BIO LTD CLASS A ORD SHS G9TY5A101   16,651,800 2,523,000 SH   SOLE   2,523,000 0 0