0001855655-24-000005.txt : 20240515 0001855655-24-000005.hdr.sgml : 20240515 20240515125710 ACCESSION NUMBER: 0001855655-24-000005 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20240331 FILED AS OF DATE: 20240515 DATE AS OF CHANGE: 20240515 EFFECTIVENESS DATE: 20240515 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Paradigm Biocapital Advisors LP CENTRAL INDEX KEY: 0001855655 ORGANIZATION NAME: IRS NUMBER: 851451055 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-21950 FILM NUMBER: 24948822 BUSINESS ADDRESS: STREET 1: 767 THIRD AVENUE, 17TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10017 BUSINESS PHONE: 646-970-2123 MAIL ADDRESS: STREET 1: 767 THIRD AVENUE, 17TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10017 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE false true false 0001855655 XXXXXXXX 03-31-2024 03-31-2024 Paradigm Biocapital Advisors LP

767 THIRD AVENUE, 17TH FLOOR NEW YORK NY 10017

13F HOLDINGS REPORT 028-21950 000312544 801-120338 N David Kim 646-970-2568 David Kim New York NY 05-15-2024 0 34 2840751736 false INFORMATION TABLE 2 PARADIGM_13F_03312024.xml AGIOS PHARMACEUTICALS INC COM 00847X104 11696000 400000 SH SOLE 400000 0 0 ALPINE IMMUNE SCIENCES INC COM 02083G100 84082901 2121163 SH SOLE 2121163 0 0 APOGEE THERAPEUTICS INC COM 03770N101 21928500 330000 SH SOLE 330000 0 0 ARCELLX INC COMMON STOCK 03940C100 265548507 3818095 SH SOLE 3818095 0 0 ARGENX SE SPONSORED ADR 04016X101 217380686 552120 SH SOLE 552120 0 0 ARVINAS INC COM 04335A105 107944517 2614935 SH SOLE 2614935 0 0 ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 76787104 507952 SH SOLE 507952 0 0 AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100 40996623 6425803 SH SOLE 6425803 0 0 BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108 80844299 3246759 SH SOLE 3246759 0 0 CARGO THERAPEUTICS INC COM 14179K101 3302445 147959 SH SOLE 147959 0 0 CARIBOU BIOSCIENCES INC COM 142038108 11167267 2172620 SH SOLE 2172620 0 0 CEREVEL THERAPEUTICS HLDNG I COM 15678U128 98510573 2330508 SH SOLE 2330508 0 0 COMPASS PATHWAYS PLC SPONSORED ADS 20451W101 19893020 2390988 SH SOLE 2390988 0 0 CRINETICS PHARMACEUTICALS IN COM 22663K107 146269500 3124749 SH SOLE 3124749 0 0 CULLINAN ONCOLOGY INC COM 230031106 22970176 1348015 SH SOLE 1348015 0 0 DISC MEDICINE INC COM 254604101 148795299 2389902 SH SOLE 2389902 0 0 EDGEWISE THERAPEUTICS INC COM 28036F105 44621844 2446373 SH SOLE 2446373 0 0 IMMATICS N.V SHS N44445109 29626723 2818908 SH SOLE 2818908 0 0 IMMUNOCORE HLDGS PLC ADS 45258D105 116166440 1787176 SH SOLE 1787176 0 0 IMMUNOVANT INC COM 45258J102 25817435 799054 SH SOLE 799054 0 0 KURA ONCOLOGY INC COM 50127T109 66877805 3135387 SH SOLE 3135387 0 0 KYVERNA THERAPEUTICS INC COM 501976104 1242000 50000 SH SOLE 50000 0 0 LEGEND BIOTECH CORP SPONSORED ADS 52490G102 111170717 1982006 SH SOLE 1982006 0 0 NUVALENT INC COM 670703107 313713255 4177830 SH SOLE 4177830 0 0 OLEMA PHARMACEUTICALS INC COM 68062P106 89468752 7903600 SH SOLE 7903600 0 0 REVOLUTION MEDICINES INC COM 76155X100 93949644 2914975 SH SOLE 2914975 0 0 SAREPTA THERAPEUTICS INC COM 803607100 139602673 1078346 SH SOLE 1078346 0 0 TARSUS PHARMACEUTICALS INC COM 87650L103 104084808 2863406 SH SOLE 2863406 0 0 VAXCYTE INC COM 92243G108 84704058 1239995 SH SOLE 1239995 0 0 VIRIDIAN THERAPEUTICS INC COM 92790C104 88100164 5031420 SH SOLE 5031420 0 0 VOR BIOPHARMA INC COM 929033108 15303784 6457293 SH SOLE 6457293 0 0 XENON PHARMACEUTICALS INC COM 98420N105 106973826 2484874 SH SOLE 2484874 0 0 Y-MABS THERAPEUTICS INC COM 984241109 36318499 2233610 SH SOLE 2233610 0 0 ZENTALIS PHARMACEUTICALS INC COM 98943L107 14891892 944917 SH SOLE 944917 0 0