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Note 13 - Segment Reporting (Tables)
12 Months Ended
Dec. 31, 2024
Notes Tables  
Schedule of Segment Reporting Information, by Segment [Table Text Block]
  Years Ended 
  December 31,  
  2024  2023 
Total revenue $  $50,000 
Less: Significant and other segment expenses        
Research and development        
PIPE-791  11,257   11,181 
PIPE-307  11,249   4,565 
CTX-343  2,460   742 
Discovery programs  4,789   3,457 
Unallocated internal costs  8,667   7,658 
General and administrative  12,472   6,320 
Interest income  8,905   4,606 
Other segment items (1)  (269)  2,037 
Net income (loss) $(42,258) $22,270