SCHEDULE 13G/A 0001104659-25-014190 0001502725 XXXXXXXX LIVE 1 Common stock, par value $0.0001 per share 03/31/2025 0001854270 Senti Biosciences, Inc. 81726A209 2 Corporate Drive, First Floor South San Francisco CA 94080 Rule 13d-1(c) NANTAHALA CAPITAL PARTNERS LIMITED PARTNERSHIP MA 0.00 502500.00 0.00 502500.00 502500.00 N 1.9 PN Senti Biosciences, Inc. 2 Corporate Drive, First Floor South San Francisco, CA, 94080 NANTAHALA CAPITAL PARTNERS LIMITED PARTNERSHIP ("Nantahala") 130 Main St. 2nd Floor, New Canaan, CT 06840 Nantahala is a Massachusetts limited partnership. Y As of March 31, 2025, Nantahala may be deemed to be the beneficial owner of 502,500 Shares. The 502,500 Shares includes 301,500 Shares which may be acquired by the Reporting Persons within sixty days through the exercise of warrants. As of March 31, 2025, each of the Reporting Persons may be deemed to be the beneficial owner of 1.9% of the total number of Shares outstanding, based on 26,004,266 shares outstanding. 0 502,500 0 502,500 N Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. NANTAHALA CAPITAL PARTNERS LIMITED PARTNERSHIP /s/ Taki Vasilakis 05/15/2025 /s/ Wilmot B. Harkey 05/15/2025 /s/ Daniel Mack 05/15/2025