X0306 4 2022-07-18 0 0001854270 Senti Biosciences, Inc. SNTI 0001816676 Rajangam Kanya C/O SENTI BIOSCIENCES, INC. 2 CORPORATE DRIVE FIRST FLOOR SOUTH SAN FRANCISCO CA 94080 0 1 0 0 Chief Medical & Devt. Officer Stock Option (Right to Buy) 1.80 2022-07-18 4 A 0 327750 0.00 A 2032-07-17 Common Stock 327750 327750 D 25% of the shares underlying this option vest on July 5, 2023 and the remainder vest in 36 substantially equal monthly installments thereafter, subject to the reporting person's continued service through the applicable vesting date. /s/ Mike Rhee, attorney-in-fact 2022-07-20