Exhibit 107

FORM F-1

REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933

(Form Type)

RELIEF THERAPEUTICS HOLDING SA

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered and Carry Forward Securities

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price (2)

Fee Rate

Amount of Registration Fee (3)

Carry Forward Form Type

Carry Forward File Number

Carry Forward Initial effective date

Filing Fee Previously Paid In Connection with Unsold Securities to be Carried Forward

Newly Registered Securities

Fees to Be Paid

Equity

Common Stock, nominal value CHF 0.01 per share (1)

Rule 457(o)

$20,000,000

0.0000927

$1,854.00

Fees Previously Paid

Carry Forward Securities

Carry Forward Securities

Total Offering Amounts

$20,000,000

$1,854.00

Total Fees Previously Paid

0

Total Fee Offsets

0

Net Fee Due

$1,854.00

(1) All ordinary shares will be in the form of American Depositary Shares, or ADSs, with each ADS representing 150 ordinary shares of the Registrant. ADSs issuable upon despot of the ordinary shares registered hereby have been registered pursuant to a sperate registration statement on Form F-6.

(2) Estimated solely for computing the amount of the registration fee pursuant to Rule 457(o) under the Securities Act of 1933, as amended. Includes the aggregate offering price of additional ordinary shares represented by ADSs, which the underwriters have the option to purchase to cover over-allotments, if any. See “Underwriting” in the Form F-1.

(3) Calculated pursuant to Rule 457(o) under the securities Act of 1933, as amended, based on an estimate of the proposed maximum aggregate offering price.