X0306 4 2021-12-27 0 0001787306 Arcutis Biotherapeutics, Inc. ARQT 0001853327 Burrows Scott L C/O ARCUTIS BIOTHERAPEUTICS, INC. 3027 TOWNSGATE ROAD, SUITE 300 WESTLAKE VILLAGE CA 91631 0 1 0 0 Chief Financial Officer Common Stock 2021-12-27 4 S 0 12560 20.0748 D 22679 D Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person. Includes 5,800 Restricted Stock Units ("RSUs"). The Reporting Person is entitled to receive one (1) share of common stock for each one (1) RSU upon the vesting thereof. The transaction was executed in multiple trades in prices ranging from $19.88 to $20.31, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. /s/ Scott L. Burrows 2021-12-28