X0508 4 2023-11-28 0000922247 Cyclo Therapeutics, Inc. CYTH 0001852018 CONKLING WILLIAM C/O CYCLO THERAPEUTICS, INC. 6714 NW 16TH STREET, SUITE B GAINESVILLE FL 32653 1 0 Common Stock 2023-11-28 4 A 0 7466 0 A 9915 D Represents the grant of fully-vested shares of common stock that the Reporting Person elected to receive in lieu of cash compensation under the Issuer's non-employee directorcompensation policy. Grant reflects director compensation for the third quarter of 2023. The number of shares received in lieu of cash was calculated based on the closing price of $1.34per share of common stock on November 28, 2023. /s/ William Conkling 2023-11-29