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Condensed Consolidated Statements of Stockholders' Equity (Deficit) (Unaudited) - USD ($)
$ in Thousands
Total
Series A Convertible Preferred Stock
Series A-1 Convertible Preferred Stock
Common Stock
Additional Paid-in Capital
Accumulated Other Comprehensive Loss
Accumulated Deficit
Balance at Dec. 31, 2020 $ (30,654)       $ 1,847   $ (32,501)
Balance, shares at Dec. 31, 2020       2,059,157      
Temporary equity, Issuance of preferred stock upon modification and conversion of notes     $ 38,911        
Temporary equity, Issuance of preferred stock upon modification and conversion of notes, shares     12,713,585        
Issuance of preferrred stock upon modification and conversion of notes 1,735       1,735    
Temporary equity, Acquisition of Oppilan and Zomagen     $ 18,526        
Temporary equity, Acquisition of Oppilan and Zomagen, shares     6,052,911        
Acquisition of Oppilan and Zomagen 2,820       2,820    
Acquisition of Oppilan and Zomagen, shares       818,798      
Temporary equity, Issuance of preferred stock and common stock, net of legal fees   $ 112,301          
Temporary equity, Issuance of preferred stock and common stock, net of legal fees, shares   12,533,905          
Issuance of preferred stock and common stock, net of legal fees         1,552   (1,552)
Issuance of preferred stock and common stock, net of legal fees, shares       507,133      
Temporary equity, Conversion of tranche liability to Series A preferred stock and common stock   $ 3,978          
Conversion of tranche liability to Series A preferred stock and common stock 3,058       3,058    
Conversion of tranche liability to Series A preferred stock and common stock, shares       507,133      
Issuance of common stock upon exercise of stock options 25       25    
Issuance of common stock upon exercise of stock options, shares       12,540      
Issuance of common stock upon vesting of restricted common stock, shares       51,212      
Stock-based compensation expense 368       368    
Foreign currency translation (12)         $ (12)  
Net loss (53,204)           (53,204)
Temporary equity, Balance at Jun. 30, 2021   $ 116,279 $ 57,437        
Temporary equity, Balance, shares at Jun. 30, 2021   12,533,905 18,766,496        
Balance at Jun. 30, 2021 (75,864)       11,405 (12) (87,257)
Balance, shares at Jun. 30, 2021       3,955,973      
Temporary equity, Balance at Mar. 31, 2021   $ 55,301 $ 57,437        
Temporary equity, Balance, shares at Mar. 31, 2021   6,283,401 18,766,496        
Balance at Mar. 31, 2021 (63,662)       8,034 2 (71,698)
Balance, shares at Mar. 31, 2021       3,410,694      
Temporary equity, Issuance of preferred stock and common stock, net of legal fees   $ 57,000          
Temporary equity, Issuance of preferred stock and common stock, net of legal fees, shares   6,250,504          
Temporary equity, Conversion of tranche liability to Series A preferred stock and common stock   $ 3,978          
Conversion of tranche liability to Series A preferred stock and common stock 3,058       3,058    
Conversion of tranche liability to Series A preferred stock and common stock, shares       507,133      
Issuance of common stock upon exercise of stock options 25       25    
Issuance of common stock upon exercise of stock options, shares       12,540      
Issuance of common stock upon vesting of restricted common stock, shares       25,606      
Stock-based compensation expense 288       288    
Foreign currency translation (14)         (14)  
Net loss (15,559)           (15,559)
Temporary equity, Balance at Jun. 30, 2021   $ 116,279 $ 57,437        
Temporary equity, Balance, shares at Jun. 30, 2021   12,533,905 18,766,496        
Balance at Jun. 30, 2021 (75,864)       11,405 (12) (87,257)
Balance, shares at Jun. 30, 2021       3,955,973      
Balance at Dec. 31, 2021 279,199     $ 5 397,051 (58) (117,799)
Balance, shares at Dec. 31, 2021       50,408,830      
Issuance of common stock upon exercise of stock options $ 220       220    
Issuance of common stock upon exercise of stock options, shares 417,332     417,332      
Issuance of common stock upon vesting of restricted common stock, shares       63,830      
Shares issued under employee stock purchase plan $ 115       115    
Shares issued under employee stock purchase plan, shares       9,074      
Adjustment to offering expenses in the initial public offering 26       26    
Stock-based compensation expense 7,575       7,575    
Unrealized loss on marketable securities (1,221)         (1,221)  
Foreign currency translation (12)         (12)  
Net loss (42,750)           (42,750)
Balance at Jun. 30, 2022 243,152     $ 5 404,987 (1,291) (160,549)
Balance, shares at Jun. 30, 2022       50,899,066      
Balance at Mar. 31, 2022 259,123     $ 5 400,607 (958) (140,531)
Balance, shares at Mar. 31, 2022       50,729,820      
Issuance of common stock upon exercise of stock options 134       134    
Issuance of common stock upon exercise of stock options, shares       118,918      
Issuance of common stock upon vesting of restricted common stock, shares       41,254      
Shares issued under employee stock purchase plan 115       115    
Shares issued under employee stock purchase plan, shares       9,074      
Stock-based compensation expense 4,131       4,131    
Unrealized loss on marketable securities (279)         (279)  
Foreign currency translation (54)         (54)  
Net loss (20,018)           (20,018)
Balance at Jun. 30, 2022 $ 243,152     $ 5 $ 404,987 $ (1,291) $ (160,549)
Balance, shares at Jun. 30, 2022       50,899,066