X0306 4 2022-08-23 0 0001851194 Ventyx Biosciences, Inc. VTYX 0001394208 Krueger Christopher W C/O VENTYX BIOSCIENCES, INC. 662 ENCINITAS BLVD, SUITE 250 ENCINITAS CA 92024 0 1 0 0 Chief Business Officer Common Stock 2022-08-23 4 M 0 96778 0.20 A 280109 D Common Stock 2022-08-23 4 M 0 72583 0.20 A 352692 D Stock Option (right to buy) 0.20 2022-08-23 4 M 0 96778 0.00 D 2029-03-27 Common Stock 96778 0 D Stock Option (right to buy) 0.20 2022-08-23 4 M 0 72583 0.00 D 2030-05-01 Common Stock 72583 24195 D Option granted under the Issuer's 2019 Equity Incentive Plan, as amended (the "2019 Plan"). Subject to the Reporting Person continuing to be a Service Provider (as defined in the 2019 Plan) through each applicable date, one thirty-sixth (1/36th) of the shares subject to the option shall vest each month following the Vesting Commencement Date on the same day of the month as the Vesting Commencement Date (and if there is no corresponding day, on the last day of the month). "Vesting Commencement Date" shall mean February 6, 2019. Option granted under the 2019 Plan. Subject to the Reporting Person continuing to be a Service Provider (as defined in the 2019 Plan) through each applicable date, one thirty-sixth (1/36th) of the shares subject to the option shall vest each month following the Vesting Commencement Date on the same day of the month as the Vesting Commencement Date (and if there is no corresponding day, on the last day of the month). "Vesting Commencement Date" shall mean May 1, 2020. /s/ Christopher Krueger 2022-08-24