Business - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands		3 Months Ended
	Jun. 01, 2021	Mar. 31, 2022	Mar. 31, 2021	Jan. 31, 2022	Dec. 31, 2021
Class Of Stock [Line Items]
Convertible Preferred Stock, Shares Issued upon Conversion		38,826,388
Accumulated deficit		$ (173,902)			$ (151,896)
Net loss		(22,006)	$ (23,921)
Cash Cash Equivalents And Short Term Investments		$ 316,000
Period of operations sufficient to fund		12 months
Convertible Preferred Stock
Class Of Stock [Line Items]
Convertible Preferred Stock, Shares Issued upon Conversion				1,000
IPO
Class Of Stock [Line Items]
Stock Issued During Period Shares New Issues	11,730,000
Shares Issued, Price Per Share	$ 22.00
IPO | Convertible Debt | 2021 Notes
Class Of Stock [Line Items]
Conversion of convertible securities	7,531,777
IPO | Convertible Preferred Stock
Class Of Stock [Line Items]
Convertible Preferred Stock, Shares Issued upon Conversion	38,826,388
IPO | Convertible Preferred Stock | Common Stock
Class Of Stock [Line Items]
Outstanding warrant to purchase convertible preferred stock	129,156
Singular Genomics Systems
Class Of Stock [Line Items]
Proceeds from initial public offering, net of issuance costs		$ 237,200
Payments for Underwriting Expense		$ 20,900
Singular Genomics Systems | Over-Allotment Option
Class Of Stock [Line Items]
Stock Issued During Period Shares New Issues		1,530,000