X0306 4 2021-07-30 1 0001850838 Omega Therapeutics, Inc. OMGA 0001340097 Invus Public Equities, L.P. 750 LEXINGTON AVENUE 30TH FLOOR NEW YORK NY 10022 0 0 1 0 0001218180 Artal International S.C.A. VALLEY PARK, 44 RUE DE LA VALLEE LUXEMBOURG N4 L-2661 LUXEMBOURG 0 0 1 0 0001522131 Artal International Management S.A. VALLEY PARK, 44 RUE DE LA VALLEE LUXEMBOURG N4 L-2661 LUXEMBOURG 0 0 1 0 0001053906 Artal Group S.A. VALLEY PARK, 44 RUE DE LA VALLEE LUXEMBOURG N4 L-2661 LUXEMBOURG 0 0 1 0 0001283968 Westend S.A. VALLEY PARK, 44 RUE DE LA VALLEE LUXEMBOURG N4 L-2661 LUXEMBOURG 0 0 1 0 0001841311 Wittouck Amaury VALLEY PARK, 44 RUE DE LA VALLEE LUXEMBOURG N4 L-2661 LUXEMBOURG 0 0 1 0 0001460840 Stichting Administratiekantoor Westend CLAUDE DEBUSSYLAAN, 46 1082 MD AMSTERDAM THE NETHERLANDS P7 NETHERLANDS 0 0 1 0 0001766952 Artal Treasury Ltd P.O. BOX 165 SUITE 4, BOROUGH HOUSE, RUE DU PRE ST. PETER PORT GY1 3JJ 0 0 1 0 0001340096 Invus Public Equities Advisors, LLC 750 LEXINGTON AVENUE 30TH FLOOR NEW YORK NY 10022 0 0 1 0 Common Stock 2021-07-30 4 P 0 75000 16.1379 A 75000 D Common Stock 2021-08-03 4 C 0 1323530 A 1398530 D Common Stock 2021-08-03 4 P 0 875000 17.00 A 2273530 D Series C Convertible Preferred Stock 2021-08-03 4 C 0 5000000 D Common Stock 1323530 0 D The shares reported as purchased on July 30, 2021 were purchased in several transactions at actual purchase prices ranging from $16.00 to $16.2068 per share, in each case exclusive of any fees, commissions or other expenses. The price reported reflects the weighted average purchase price for the transactions. The Reporting Persons undertake to provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares purchased at each separate price. The shares are held directly by Invus Public Equities, L.P. The general partner of Invus Public Equities, L.P. is Invus Public Equities Advisors, LLC. Artal Treasury Ltd is the managing member of Invus Public Equities Advisors, LLC. Artal Treasury Ltd is a wholly owned subsidiary of the Geneva branch of Artal International S.C.A. The managing partner of Artal International S.C.A. is Artal International Management S.A., which is a wholly owned subsidiary of Artal Group S.A. Westend S.A. is the parent company of Artal Group, S.A., and the majority stockholder of Westend S.A. is Stichting Administratiekantoor Westend ("Stichting"). (Continued from Footnote 2) Mr. Amaury Wittouck is the sole member of the board of Stichting. Each of the Reporting Persons, other than Invus Public Equities L.P., disclaims beneficial ownership of the securities held by the other Reporting Persons, except to the extent of such reporting person's pecuniary interest therein, and, pursuant to Rule 16a-1(a)(4) under the Exchange Act, each of the reporting persons (other than to the extent it directly holds securities reported herein) states that the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 of the Exchange Act or for any other purpose. The shares of Issuer's preferred stock had no expiration date and were convertible at the holder's election into Issuer's common stock at a conversion ratio of 1-to-0.264706. The preferred stock automatically converted into shares of the Issuer's common stock, for no additional consideration, upon the closing of the Issuer's initial public offering. Invus Public Equities, L.P., By: Invus Public Equities Advisors, LLC, its General Partner, By: /s/ Raymond Debbane, President 2021-08-03 Invus Public Equities Advisors, LLC, By: /s/ Raymond Debbane, President 2021-08-03 Artal Treasury Ltd, By: /s/ Keith Le Poidevin, Director 2021-08-03 Artal International S.C.A., By: Artal International Management S.A., its Managing Partner, By: /s/ Anne Goffard, Managing Director 2021-08-03 Artal International Management S.A., By: /s/ Anne Goffard, Managing Director 2021-08-03 Artal Group S.A., By: /s/ Anne Goffard, Authorized Person 2021-08-03 Westend S.A., By: /s/ Anne Goffard, Director 2021-08-03 Stichting Administratiekantoor Westend, By: /s/ Amaury Wittouck, Sole Member of the Board 2021-08-03 /s/ Amaury Wittouck 2021-08-03