Significant Accounting Policies - Summary of Accrued expense (Details) - USD ($) $ in Thousands	Jun. 30, 2025	Dec. 31, 2024
Accounting Policies [Abstract]
Compensation	$ 7,233	$ 10,217
Severance	663	1,236
Clinical study related costs	13,576	16,452
Facility related costs	871	369
Accrued legal costs	1,068	395
Accrued consulting and professional fees	297	557
Other accrued expenses	1,208	1,911
Total accrued expenses and other	$ 24,916	$ 31,137