Revenue recognition - Total transaction price (Details) $ in Thousands	9 Months Ended
	Sep. 30, 2022 USD ($)
Disaggregation of Revenue [Line Items]
Total	$ 118,509
Less current portion of deferred revenue	(7,571)
Total long-term deferred revenue	110,938
Transaction price
Disaggregation of Revenue [Line Items]
Total	123,187
Total long-term deferred revenue	123,187
Cumulative collaboration revenue recognized
Disaggregation of Revenue [Line Items]
Cumulative collaboration revenue recognized	(4,678)
Option rights
Disaggregation of Revenue [Line Items]
Total	109,045
Option rights | Transaction price
Disaggregation of Revenue [Line Items]
Total	109,045
Research and development services
Disaggregation of Revenue [Line Items]
Total	9,464
Research and development services | Transaction price
Disaggregation of Revenue [Line Items]
Total	14,142
Research and development services | Cumulative collaboration revenue recognized
Disaggregation of Revenue [Line Items]
Cumulative collaboration revenue recognized	$ (4,678)