Revenue recognition (Details) $ / shares in Units, $ in Thousands		3 Months Ended			9 Months Ended
	Jan. 07, 2022 USD ($) Program item $ / shares shares	Mar. 31, 2022 USD ($)	Sep. 30, 2021 USD ($)	Jun. 30, 2021 USD ($)	Sep. 30, 2022 USD ($) $ / shares	Sep. 30, 2021 USD ($)	Dec. 31, 2021 $ / shares	Jun. 22, 2021 $ / shares	Feb. 25, 2021 $ / shares
Common stock, par value | $ / shares					$ 0.0001		$ 0.0001	$ 0.0001	$ 0.0001
Aggregate purchase price					$ 250	$ 130
Aggregate purchase price excluding premium		$ 26,813	$ 217	$ 221,185
Total transaction price					$ 123,187
Collaboration Agreement
Number of collaboration programs | Program	2
Additional number of collaboration programs | Program	2
Upfront cash payment receivable	$ 100
Milestone payments receivable upon achievement of certain development and regulatory milestones	235
Sales-based milestone payments	$ 500
Termination of Royalty term	12 years
Common stock issued | shares	2,160,760
Common stock, par value | $ / shares	$ 23.14
Aggregate purchase price	$ 50
Common stock, premium per share | $ / shares	$ 7.82
Premium amount of common stock	$ 23,200
Aggregate purchase price excluding premium	$ 26,800
Number of Commitments | item	4
FCDI Collaboration Agreement | Collaboration Agreement
Upfront cash payment receivable	$ 10,000