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Collaboration (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Dec. 31, 2021
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Total revenue $ 5,655 $ 2,852 $ 11,291 $ 5,179  
License          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Total revenue $ 1,100   $ 2,200    
Pfizer | License          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Upfront payment         $ 8,000
Additional amounts to be received         10,000
Pfizer | Clinical | Minimum          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Milestone payments to be received         20,000
Pfizer | Clinical | Maximum          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Milestone payments to be received         55,000
Pfizer | Sales Milestones | Minimum          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Milestone payments to be received         60,000
Pfizer | Sales Milestones | Maximum          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Milestone payments to be received         $ 180,000
Royalty percentage         1.00%