X0206 3 2021-05-27 0 0001847903 Centessa Pharmaceuticals plc CNTA 0001861844 GOYAL ARJUN C/O CENTESSA PHARMACEUTICALS PLC 3RD FL., 1 ASHLEY RD, ALTRINCHAM CHESHIRE X0 WA14 2DT UNITED KINGDOM 1 0 0 0 Series A Preferred Shares Ordinary Shares 3095909 I See footnote Series A Preferred Shares Ordinary Shares 85909 I See footnote Immediately prior to the closing of the initial public offering closing, Series A Preferred Shares will automatically convert on a one-to-one basis into Ordinary Shares without payment or further consideration. The resulting number of Ordinary Shares of the Issuer are shown in Column 3. The Series A Preferred Shares have no expiration date. Ordinary Shares may be represented by American Depositary Shares, each of which currently represents one Ordinary Share. Held by Vida Ventures II, LLC ("Vida II Main Fund"). VV Manager II, LLC ("VV Manager II") is the manager of Vida II Main Fund. The Reporting Person is a member of the investment committee of VV Manager II. The Reporting Person disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein. Held by Vida Ventures II-A, LLC ("Vida II Parallel Fund"). VV Manager II is the manager of Vida II Parallel Fund. The Reporting Person is a member of the investment committee of VV Manager II. The Reporting Person disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein. Exhibit 24 - Power of Attorney /s/ Marella Thorell, attorney-in-fact 2021-05-27