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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Cash flows from operating activities    
Net loss $ (294,233) $ (154,993)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 19,457 8,625
Change in fair value of derivative liability 5,406 119
Net accretion of discounts on marketable securities (3,685) (544)
Depreciation and amortization 3,152 1,284
Non-cash lease expense 60 2,010
Loss on disposal of fixed assets 5 266
Write-off of deferred offering costs   555
Loss on abandonment of right-of-use assets   645
Changes in operating assets and liabilities:    
Research and development prepaid expenses (10,763) 5,526
Other prepaid expenses and other assets (2,870) (340)
Accounts payable 8,506 (642)
Research and development accrued expenses 18,203 5,168
Other accrued expenses and current liabilities 3,542 2,490
Operating lease liabilities (1,858) (144)
Net cash used in operating activities (255,078) (129,975)
Cash flows from investing activities    
Maturities of marketable securities 128,000 76,250
Purchases of marketable securities (240,058) (11,279)
Purchases of property and equipment (1,732) (4,499)
Net cash (used in) provided by investing activities (113,790) 60,472
Cash flows from financing activities    
Proceeds from issuance of redeemable convertible preferred stock and derivative liability, net of offering costs 258,461 89,778
Proceeds from initial public offering, net of underwriter discounts and commissions and other offering costs 193,316  
Proceeds from a private placement transaction 40,000  
Proceeds from issuance of common stock upon exercise of stock options 596 453
Payments of deferred offering costs   (485)
Repurchase of unvested common stock shares issued upon early exercised stock options (6) (64)
Net cash provided by financing activities 492,367 89,682
Net increase in cash, cash equivalents and restricted cash 123,499 20,179
Cash, cash equivalents and restricted cash at beginning of period 47,133 26,954
Cash, cash equivalents and restricted cash at end of period 170,632 47,133
Supplemental disclosures:    
Conversion of 168,489,871 shares of redeemable convertible preferred stock upon the closing of initial public offering 639,237  
Settlement of derivative liability upon issuance of redeemable convertible preferred stock (14,319) (2,231)
Recognition of derivative liability upon issuance of redeemable convertible preferred stock 8,913 2,112
Vesting of early exercised stock options and unvested restricted shares of common stock 1,174 1,944
Right-of-use assets obtained in exchange for operating lease liabilities   14,255
Property and equipment acquired through tenant improvement allowance   16,691
Purchases of property and equipment in other accrued expenses and current liabilities   49
Reconciliation of cash, cash equivalents and restricted cash:    
Cash and cash equivalents 169,526 45,996
Restricted cash   113
Restricted cash, non-current 1,106 1,024
Total cash, cash equivalents and restricted cash $ 170,632 $ 47,133