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Condensed Statements of Cash Flows (unaudited) - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Cash flows from operating activities    
Net Income (Loss) $ (66,318) $ (66,819)
Adjustments to reconcile net loss to net cash used in operating activities:    
Share-based compensation expense 23,759 25,674
Depreciation expense 185 38
Accretion of discounts on short-term investments, net (8,402) (2,189)
Amortization of intangible assets 1,520 298
Amortization of operating right-of-use asset 153 188
Loss from sale of property and equipment 71 0
Gain from sale of priority review voucher 0 (108,000)
Changes in operating assets and liabilities:    
Accounts receivable, net (5,793) (9,136)
Inventory (3,152) (129)
Prepaid expenses and other current assets (1,707) (3,078)
Deposits and other long-term assets (62) 97
Accounts payable 1,828 3,868
Accrued expenses and other current liabilities (26,494) 60,548
Deferred revenue 431 0
Operating lease liability 178 (218)
Net cash used in operating activities (83,803) (98,858)
Cash flows from investing activities    
Cash paid for purchase of short-term investments (428,298) (168,761)
Proceeds from maturity of short-term investments 425,795 184,232
Cash paid for acquired intangible assets (3,500) (17,100)
Proceeds from sale of priority review voucher 0 108,000
Cash paid for purchase of property and equipment (320) (26)
Proceeds from sale of property and equipment 32 0
Net cash (used in) provided by investing activities (6,291) 106,345
Cash flows from financing activities    
Proceeds from issuance of common stock upon stock option exercises 0 372
Proceeds from issuance of common stock upon Employee Stock Purchase Plan purchase 748 973
Cash provided by financing activities 748 1,345
Net (decrease) increase in cash and cash equivalents (89,346) 8,832
Cash and cash equivalents, beginning of period 124,968 230,784
Cash and cash equivalents, end of period 35,622 239,616
Supplemental disclosure of cash flow information:    
Income taxes paid 5,316 0
Supplemental disclosures of noncash activities:    
Cash not yet paid for acquired intangible asset 2,000 0
Right-of-use asset obtained in exchange for new operating lease liabilities 230 0
Cash not yet paid for upfront license agreement payment $ 0 $ 55,000