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Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($) $ in Thousands		12 Months Ended
	Apr. 23, 2024	Dec. 31, 2024	Dec. 31, 2023
Class of Stock [Line Items]
Accounts receivable, credit losses		$ 0
Other expenses		0
Milestone Payment Capitalized, Amount		$ 9,000
Intangible asset useful life		7 years 3 months 18 days
Share Purchased		101,116,162	87,227,132
Share-based compensation arrangement by share-based payment award, fair value assumptions, expected dividend payments		$ 0
Weighted-average vesting contractual term of the award		10 years
Weighted-average vesting term of the award		10 years
Unrecognized Tax Benefits More Likely Than Not Threshold Percentage		50.00%
Viracta License Agreement
Class of Stock [Line Items]
PRV Related Obligation, Amount		$ 8,100
Payment of Milestones	$ 9,000
Ipsen License Agreement
Class of Stock [Line Items]
Aggregate Of Upfront License Fee Received		70,800
Premium Received On License Agreement		$ 7,400
Share Purchased		2,341,495
Payment to private placement		$ 40,000
Premium to volume weighted average price		17.00%
Payment of Milestones		$ 330,000
Transaction Price		$ 78,200
Individual Customer \| Sales Revenue Net \| Concentration Of Credit Risk And Other Risks And Uncertainties
Class of Stock [Line Items]
Concentration Risk, Percentage		94.30%
Individual Customer \| Accounts Receivable \| Concentration Of Credit Risk And Other Risks And Uncertainties
Class of Stock [Line Items]
Concentration Risk, Percentage		88.70%
One Customer \| Sales Revenue Net \| Concentration Of Credit Risk And Other Risks And Uncertainties
Class of Stock [Line Items]
Concentration Risk, Percentage		66.20%
One Customer \| Accounts Receivable \| Concentration Of Credit Risk And Other Risks And Uncertainties
Class of Stock [Line Items]
Concentration Risk, Percentage		64.50%
Two Customer \| Sales Revenue Net \| Concentration Of Credit Risk And Other Risks And Uncertainties
Class of Stock [Line Items]
Concentration Risk, Percentage		28.10%
Two Customer \| Accounts Receivable \| Concentration Of Credit Risk And Other Risks And Uncertainties
Class of Stock [Line Items]
Concentration Risk, Percentage		24.20%
Other Individual Customer \| Net Product Revenue And Accounts Receivable \| Concentration Of Credit Risk And Other Risks And Uncertainties \| Maximum
Class of Stock [Line Items]
Concentration Risk, Percentage		10.00%