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Segment Reporting (Tables)
12 Months Ended
Dec. 31, 2024
Segment Reporting [Abstract]  
Schedule of Segment Information

In addition to the significant expense categories included within net loss presented on the Company's Statements of Operations, see below for disaggregated amounts that comprise research and development expenses:

 

 

Year Ended
December 31,

 

 

 

2024

 

 

2023

 

 

2022

 

 

 

(in thousands)

 

External costs:

 

 

 

 

 

 

 

 

 

Third-party CRO, CMO and other third-party clinical trial costs (1)

 

$

89,400

 

 

$

71,294

 

 

$

50,175

 

License upfront payments and milestones

 

 

80,000

 

 

 

8,000

 

 

 

2,500

 

Other research and development costs

 

 

8,949

 

 

 

8,465

 

 

 

3,598

 

Internal costs:

 

 

 

 

 

 

 

 

 

Employee related expenses

 

 

49,353

 

 

 

42,762

 

 

 

29,345

 

Total research and development expenses

 

$

227,702

 

 

$

130,521

 

 

$

85,618

 

(1) Costs incurred under agreements with third-party CROs, CMOs, and other third parties that conduct clinical activities on the Company's behalf.