Commitment and Contingencies - Additional Information (Detail)	1 Months Ended	3 Months Ended
	Apr. 30, 2022 USD ($) ft²	Mar. 31, 2023 USD ($)	Mar. 31, 2022 USD ($)	Dec. 31, 2022 USD ($)
Lessee, Lease, Description [Line Items]
Amortization of operating right-of-use assets		$ 83,000	$ 47,000
Weighted Average Remaining Lease Term		1 year 8 months 12 days
Weighted Average Discount Rate Percent		9.00%
Research And Development Agreements
Lessee, Lease, Description [Line Items]
Termination and cancellation charges payable		$ 0		$ 0
Viracta License Agreement
Lessee, Lease, Description [Line Items]
Royalty fee payable		0		0
Indemnification Agreement
Lessee, Lease, Description [Line Items]
Termination and cancellation charges payable		0		$ 0
Central America
Lessee, Lease, Description [Line Items]
Operating lease term	31 months
Sublease agreement area | ft²	12,000
Operating lease payments	$ 1,100,000
Security Deposit	$ 40,000
Lease For Corporate Office Facility | Central America
Lessee, Lease, Description [Line Items]
Amortization of operating right-of-use assets		100,000	47,000,000
Operating lease payments		$ 100,000	$ 52,000,000