Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Cash flows from operating activities
Net loss	$ (142,181)	$ (72,754)	$ (43,843)
Adjustments to reconcile net loss to net cash used in operating activities:
Acquired in-process research and development assets	0	8,000	0
Share-based compensation expense	27,242	13,321	526
Depreciation expense	63	20	16
Accretion of discounts on short-term investments, net	(2,030)	0	0
Amortization of operating right-of-use assets	468	179	139
Non-cash interest expense	0	0	30
Changes in derivative tranche liabilities	0	0	30,000
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	(546)	(3,717)	(1,336)
Deposits and other long-term assets	(300)	(62)	(107)
Accounts payable	(1,484)	1,542	132
Accrued expenses and other current liabilities	9,241	5,114	1,127
Operating lease liabilities	(347)	(182)	(173)
Net cash used in operating activities	(109,874)	(48,539)	(13,489)
Cash flows from investing activities
Cash paid for purchase of short-term investments	(394,206)	0	0
Cash paid for purchase of property and equipment	(26)	0	(92)
Proceeds from maturity of short-term investment	139,158	0	0
Cash paid for acquired in-process research and development assets	0	(8,000)	0
Net cash used in investing activities	(255,074)	(8,000)	(92)
Cash flows from financing activities
Proceeds from issuance of common stock, net	161,610	167,045	0
Proceeds from issuance of common stock upon stock option exercises	3,649		0
Proceeds from issuance of common stock upon ESPP purchase	642	318	0
Net cash provided by financing activities	165,901	297,120	29,977
Net (decrease) increase in cash and cash equivalents	(199,047)	240,581	16,396
Cash and cash equivalents, beginning of period	284,309	43,728	27,332
Cash and cash equivalents, end of period	85,262	284,309	43,728
Supplemental disclosures of noncash activities
Lease liability obtained in exchange for right-of-use asset	940	0	545
Transfers to redeemable convertible noncontrolling interest	0	0	3,551
Exchange of 45,331,483 preferred, common, and incentive shares in connection with the Conversion (Note 1)	0	224,892	0
Exchange of redeemable convertible noncontrolling interest to 6,470,382 shares of common stock (Note 11)	0	3,592	0
Series A Preferred Stock [Member]
Cash flows from financing activities
Proceeds from issuance of redeemable convertible preferred shares, net of issuance costs	0		29,977
Series B Preferred Stock [Member]
Cash flows from financing activities
Proceeds from issuance of redeemable convertible preferred shares, net of issuance costs		$ 129,757	$ 0