Significant Agreements - Additional Information (Detail) - USD ($) $ in Thousands		1 Months Ended	12 Months Ended
	Dec. 16, 2019	Feb. 28, 2021	Dec. 31, 2022	Dec. 31, 2021
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Common stock issued in IPO, net of issuance costs of $16,995				$ 167,045
Common Stock [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Stock Issued During Period, Shares, New Issues				11,500,000
Common stock issued in IPO, net of issuance costs of $16,995				$ 1
Takeda Asset Agreement [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Upfront of cash payment	$ 1,000
Takeda Asset Agreement [Member] | Common Stock [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Issuance of Series A redeemable convertible preferred shares, shares	6,470,382
Takeda Asset Agreement [Member] | Series A Redeemable Convertible Preferred Stock [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Stock Issued During Period, Shares, New Issues			9,857,143
Common stock issued in IPO, net of issuance costs of $16,995	$ 9,900
Issuance of Series A redeemable convertible preferred shares, shares	9,857,143
Takeda Asset Agreement [Member] | Research and Development Expense [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Upfront payment			$ 8,000
Merck License Agreement [Member] | Research and Development Expense [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Payment of Milestones			2,500
Merck License Agreement [Member] | Research and Development Expense [Member] | Maximum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Payment of Milestones			$ 364,500
Viracta License Agreement [Member] | Maximum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Payment of Milestones		$ 54,000
Viracta License Agreement [Member] | Research and Development Expense [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Payment of Milestones		$ 3,000
Upfront of cash payment	$ 2,000